Metisergido [INN-Spanish]
Brand names,
Metisergido [INN-Spanish]
Analogs
Metisergido [INN-Spanish]
Brand Names Mixture
Metisergido [INN-Spanish]
Chemical_Formula
C21H27N3O2
Metisergido [INN-Spanish]
RX_link
http://www.rxlist.com/cgi/generic3/sansert.htm
Metisergido [INN-Spanish]
fda sheet
Metisergido [INN-Spanish]
msds (material safety sheet)
Metisergido [INN-Spanish]
Synthesis Reference
No information avaliable
Metisergido [INN-Spanish]
Molecular Weight
353.458 g/mol
Metisergido [INN-Spanish]
Melting Point
195 oC
Metisergido [INN-Spanish]
H2O Solubility
No information avaliable
Metisergido [INN-Spanish]
State
Solid
Metisergido [INN-Spanish]
LogP
1.55
Metisergido [INN-Spanish]
Dosage Forms
Tablet
Metisergido [INN-Spanish]
Indication
For the treatment of vascular headache
Metisergido [INN-Spanish]
Pharmacology
Methysergide has been shown, in vitro and in vivo, to inhibit or block the effects of serotonin, a substance which may be involved in the mechanism of vascular headaches. Serotonin has been variously described as a central neurohumoral agent or chemical mediator, as a "headache substance" acting directly or indirectly to lower pain threshold, as an intrinsic "motor hormone" of the gastrointestinal tract, and as a "hormone" involved in connective tissue reparative processes.
Metisergido [INN-Spanish]
Absorption
Rapid
Metisergido [INN-Spanish]
side effects and Toxicity
No information avaliable
Metisergido [INN-Spanish]
Patient Information
No information avaliable
Metisergido [INN-Spanish]
Organisms Affected
Humans and other mammals